Does pulmonary surfactant generally affect antimicrobial activity?
نویسندگان
چکیده
منابع مشابه
Effect of pulmonary surfactant on antimicrobial activity in vitro.
Time-kill curve experiments were performed with linezolid, doripenem, tigecycline, moxifloxacin, and daptomycin against Staphylococcus aureus and with colistin, moxifloxacin, and doripenem against Pseudomonas aeruginosa to evaluate the effect of porcine pulmonary surfactant on antimicrobial activity. Pulmonary surfactant significantly impaired the activities of moxifloxacin and colistin. When a...
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OBJECTIVES We assessed the in vitro effect of exposing various bacteria to minocycline/rifampicin-impregnated vascular catheters on the antimicrobial activity of the catheters and the antimicrobial susceptibility of tested organisms. METHODS Segments of minocycline/rifampicin-impregnated catheters were placed in agar plates inoculated with methicillin-susceptible Staphylococcus aureus (MSSA),...
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The involvement of the pulmonary surfactant system in defense of the alveoli and distal airways of the lungs is an aspect of respiratory physiology and toxicology that has been largely overlooked. The pulmonary surfactant system is absolutely critical to survival of all mammalian species, as progressive loss of surfactant leads to lung collapse and death of the organism. In recent years it has ...
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Surfactant protein B (SP-B) is secreted into the airspaces with surfactant phospholipids where it reduces surface tension and prevents alveolar collapse at end expiration. SP-B is a member of the saposin-like family of proteins, several of which have antimicrobial properties. SP-B lyses negatively charged liposomes and was previously reported to inhibit the growth of Escherichia coli in vitro; ...
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Background: Transcutaneous electrical nerve stimulation (TENS) is a noninvasive, inexpensive and safe analgesic technique used for relieving acute and chronic pain. However, despite all these advantages, there has been very little research into the therapeutic effects of TENS on brain activity. To the best of our knowledge, there is no evidence on the effect of high frequency TENS on the gamma ...
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ژورنال
عنوان ژورنال: BMC Pharmacology and Toxicology
سال: 2012
ISSN: 2050-6511
DOI: 10.1186/2050-6511-13-s1-a62